Pratique des Biostatistiques
Dernière modification: 26 avril 2011

Optimisation d'une expérience

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  • strict warning: Non-static method view::load() should not be called statically in /home/iamin/www/umdb/biostats/sites/default/modules/views/views.module on line 906.

Supposons qu'un laboratoire pharmaceutique demande à l'un de ses chercheurs de montrer qu'une molécule X provoque une augmentation de la pression sanguine chez le rat.

L'employé doit mettre toutes les chances de son côté pour démontrer cet accroissement de la pression sanguine, pour cela, il peut contrôler les paramètres suivants s'ils existent :

  PARAMETRE

COMMENT LE

MODIFIER ?

EFFET MODIFIABLE?
1 µ1 Augmenter la dose du médicament Augmentation de la distance entre les modèles
2 Variance de la population Cibler au mieux la population (rats mâles de 3 mois non stressés) Resserrement des courbes autour de leur moyenne
3 Taille d'échantillon Augmenter la taille de l'échantillon Resserrement des courbes autour de leur moyenne
4 alpha Augmenter alpha Augmentation de RH0 même si pas d'effet à observer